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Review article| Volume 82, ISSUE 6, P1199-1211, December 2002

Anal condyloma and HIV-associated anal disease

      In the United States, improved understanding and therapy against the HIV virus since 1996 has been accompanied by a substantial decrease in those diagnosed with acquired immunodeficiency syndrome (AIDS); 41,113 new cases were diagnosed during the year 2000 [
      • Anonymous
      Update: AIDS–United States, 2000.
      ,
      • Karon J.M.
      • Fleming P.L.
      • Steketee R.W.
      • et al.
      HIV in the United States at the turn of the century; an epidemic in transition.
      ]. A concurrent decrease in AIDS-related deaths, however, has increased the number of persons living with the disease to an estimated 337,731 in the year 2000 [
      • Anonymous
      Update: AIDS–United States, 2000.
      ]. Although it is more difficult to estimate, more than 900,000 people may be infected with the HIV virus [
      • Karon J.M.
      • Rosenburg P.S.
      • McQuillan G.
      • et al.
      Prevalence of HIV infection in the United States, 1984 to 1992.
      ]. Anorectal disorders occur in 5.9% to 34% of the HIV population [
      • Miles A.J.
      • Mellor C.H.
      • Gazzard B.
      • et al.
      Surgical management of anorectal disease in HIV-positive homosexuals.
      ,
      • Nadal S.R.
      • Menzione C.R.
      • Galvao Vd.M.
      • et al.
      Perianal diseases in HIV-positive patients compared with a seronegative population.
      ,
      • Safavi A.
      • Gottesman L.
      • Dailey T.
      Anorectal surgery in the HIV+ patient: update.
      ] and are often the initial reason to seek medical attention [
      • Gelb A.
      • Miller S.
      AIDS and gastroenterology.
      ].
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