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Review Article| Volume 98, ISSUE 4, P677-685, August 2018

Breast Cancer Genetics and Indications for Prophylactic Mastectomy

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      References

        • Daly M.B.
        • Pilarski R.
        • Berry M.
        • et al.
        NCCN guidelines insights: genetic/familial high-risk assessment: breast and ovarian, version 2.2017.
        J Natl Compr Canc Netw. 2017; 15: 9-20
        • Mai P.L.
        • Best A.F.
        • Peters J.A.
        • et al.
        Risks of first and subsequent cancers among TP53 mutation carriers in the National Cancer Institute Li-Fraumeni syndrome cohort.
        Cancer. 2016; 122: 3673-3681
        • Grignol V.P.
        • Agnese D.M.
        Breast cancer genetics for the surgeon: an update on causes and testing options.
        J Am Coll Surg. 2016; 222: 906-914
        • Rainville I.R.
        • Rana H.Q.
        Next-generation sequencing for inherited breast cancer risk: counseling through the complexity.
        Curr Oncol Rep. 2014; 16: 371
        • Katki H.A.
        • Gail M.H.
        • Greene M.H.
        Breast-cancer risk in BRCA-mutation-negative women from BRCA-mutation-positive families.
        Lancet Oncol. 2007; 8: 1042-1043
        • Korde L.A.
        • Mueller C.M.
        • Loud J.T.
        • et al.
        No evidence of excess breast cancer risk among mutation-negative women from BRCA mutation-positive families.
        Breast Cancer Res Treat. 2011; 125: 169-173
        • Metcalfe K.A.
        • Finch A.
        • Poll A.
        • et al.
        Breast cancer risks in women with a family history of breast or ovarian cancer who have tested negative for a BRCA1 or BRCA2 mutation.
        Br J Cancer. 2009; 100: 421-425
        • Ludwig K.K.
        • Neuner J.
        • Butler A.
        • et al.
        Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review.
        Am J Surg. 2016; 212: 660-669
        • Hartmann L.C.
        • Schaid D.J.
        • Woods J.E.
        • et al.
        Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer.
        N Engl J Med. 1999; 340: 77-84
        • Hartmann L.C.
        • Sellers T.A.
        • Schaid D.J.
        • et al.
        Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers.
        J Natl Cancer Inst. 2001; 93: 1633-1637
        • Meijers-Heijboer H.
        • van Geel B.
        • van Putten W.L.
        • et al.
        Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation.
        N Engl J Med. 2001; 345: 159-164
        • Domchek S.M.
        • Friebel T.M.
        • Singer C.F.
        • et al.
        Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality.
        JAMA. 2010; 304: 967-975
        • Yao K.
        • Liederbach E.
        • Tang R.
        • et al.
        Nipple-sparing mastectomy in BRCA1/2 mutation carriers: an interim analysis and review of the literature.
        Ann Surg Oncol. 2015; 22: 370-376
        • Peled A.W.
        • Irwin C.S.
        • Hwang E.S.
        • et al.
        Total skin-sparing mastectomy in BRCA mutation carriers.
        Ann Surg Oncol. 2014; 21: 37-41
        • Manning A.T.
        • Wood C.
        • Eaton A.
        • et al.
        Nipple-sparing mastectomy in patients with BRCA1/2 mutations and variants of uncertain significance.
        Br J Surg. 2015; 102: 1354-1359
        • Kurian A.W.
        • Lichtensztajn D.Y.
        • Keegan T.H.
        • et al.
        Use of and mortality after bilateral mastectomy compared with other surgical treatments for breast cancer in California, 1998-2011.
        JAMA. 2014; 312: 902-914
        • Arrington A.K.
        • Jarosek S.L.
        • Virnig B.A.
        • et al.
        Patient and surgeon characteristics associated with increased use of contralateral prophylactic mastectomy in patients with breast cancer.
        Ann Surg Oncol. 2009; 16: 2697-2704
        • Yao K.
        • Sisco M.
        • Bedrosian I.
        Contralateral prophylactic mastectomy: current perspectives.
        Int J Womens Health. 2016; 8: 213-223
        • Jagsi R.
        • Hawley S.T.
        • Griffith K.A.
        • et al.
        Contralateral prophylactic mastectomy decisions in a population-based sample of patients with early-stage breast cancer.
        JAMA Surg. 2017; 152: 274-282
        • Nichols H.B.
        • Berrington de González A.
        • Lacey Jr., J.V.
        • et al.
        Declining incidence of contralateral breast cancer in the United States from 1975 to 2006.
        J Clin Oncol. 2011; 29: 1564-1569
        • Reiner A.S.
        • John E.M.
        • Brooks J.D.
        • et al.
        Risk of asynchronous contralateral breast cancer in noncarriers of BRCA1 and BRCA2 mutations with a family history of breast cancer: a report from the Women's Environmental Cancer and Radiation Epidemiology Study.
        J Clin Oncol. 2013; 31: 433-439
        • Graeser M.K.
        • Engel C.
        • Rhiem K.
        • et al.
        Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers.
        J Clin Oncol. 2009; 27: 5887-5892
        • Cybulski C.
        • Kluzniak W.
        • Huzarski T.
        • et al.
        Clinical outcomes in women with breast cancer and a PALB2 mutation: a prospective cohort analysis.
        Lancet Oncol. 2015; 16: 638-644
        • Liederbach E.
        • Piro R.
        • Hughes K.
        • et al.
        Clinicopathologic features and time interval analysis of contralateral breast cancers.
        Surgery. 2015; 158: 676-685
        • Metcalfe K.
        • Gershman S.
        • Ghadirian P.
        • et al.
        Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis.
        BMJ. 2014; 348: g226
        • Evans D.G.
        • Ingham S.L.
        • Baildam A.
        • et al.
        Contralateral mastectomy improves survival in women with BRCA1/2-associated breast cancer.
        Breast Cancer Res Treat. 2013; 140: 135-142
        • Craft R.O.
        • Colakoglu S.
        • Curtis M.S.
        • et al.
        Patient satisfaction in unilateral and bilateral breast reconstruction [outcomes article].
        Plast Reconstr Surg. 2011; 127: 1417-1424
        • Koslow S.
        • Pharmer L.A.
        • Scott A.M.
        • et al.
        Long-term patient-reported satisfaction after contralateral prophylactic mastectomy and implant reconstruction.
        Ann Surg Oncol. 2013; 20: 3422-3429
        • Eck D.L.
        • Perdikis G.
        • Rawal B.
        • et al.
        Incremental risk associated with contralateral prophylactic mastectomy and the effect on adjuvant therapy.
        Ann Surg Oncol. 2014; 21: 3297-3303
        • Osman F.
        • Saleh F.
        • Jackson T.D.
        • et al.
        Increased postoperative complications in bilateral mastectomy patients compared to unilateral mastectomy: an analysis of the NSQIP database.
        Ann Surg Oncol. 2013; 20: 3212-3217
        • Silva A.K.
        • Lapin B.
        • Yao K.A.
        • et al.
        The effect of contralateral prophylactic mastectomy on perioperative complications in women undergoing immediate breast reconstruction: a NSQIP analysis.
        Ann Surg Oncol. 2015; 22: 3474-3480
        • Gopie J.P.
        • Mureau M.A.
        • Seynaeve C.
        • et al.
        Body image issues after bilateral prophylactic mastectomy with breast reconstruction in healthy women at risk for hereditary breast cancer.
        Fam Cancer. 2013; 12: 479-487
        • Brandberg Y.
        • Sandelin K.
        • Erikson S.
        • et al.
        Psychological reactions, quality of life, and body image after bilateral prophylactic mastectomy in women at high risk for breast cancer: a prospective 1-year follow-up study.
        J Clin Oncol. 2008; 26: 3943-3949
        • Frost M.H.
        • Schaid D.J.
        • Sellers T.A.
        • et al.
        Long-term satisfaction and psychological and social function following bilateral prophylactic mastectomy.
        JAMA. 2000; 284: 319-324
        • Boughey J.C.
        • Hoskin T.L.
        • Hartmann L.C.
        • et al.
        Impact of reconstruction and reoperation on long-term patient-reported satisfaction after contralateral prophylactic mastectomy.
        Ann Surg Oncol. 2015; 22: 401-408
        • Lowry K.P.
        • Lee J.M.
        • Kong C.Y.
        • et al.
        Annual screening strategies in BRCA1 and BRCA2 gene mutation carriers: a comparative effectiveness analysis.
        Cancer. 2012; 118: 2021-2030
        • Brem R.F.
        • Lenihan M.J.
        • Lieberman J.
        • et al.
        Screening breast ultrasound: past, present, and future.
        AJR Am J Roentgenol. 2015; 204: 234-240
        • Dunn B.K.
        • Ford L.G.
        Breast cancer prevention: results of the National Surgical Adjuvant Breast and Bowel Project (NSABP) breast cancer prevention trial (NSABP P-1: BCPT).
        Eur J Cancer. 2000; 36: S49-S50
        • Vogel V.G.
        The NSABP study of tamoxifen and raloxifene (STAR) trial.
        Expert Rev Anticancer Ther. 2009; 9: 51-60
        • Goss P.E.
        • Ingle J.N.
        • Ales-Martinez J.E.
        • et al.
        Exemestane for breast-cancer prevention in postmenopausal women.
        N Engl J Med. 2011; 364: 2381-2391